ACUTE HEART FAILURE

Unmet clinical needs

Heart failure is the most critical and costly public health crisis — the leading cause of death and the largest healthcare costs in the US and EU. (ref. 1-4)

Acute decompensated heart failure (ADHF) is a cardiac crisis where the heart fails to pump blood effectively, causing fluid to rapidly flood the lungs and body.

Pulmonary artery catheters (PACs) are the standard of care for patients with ADHF.

PACs are inserted into a heart to directly measure hemodynamic data to assess heart function.

Today’s legacy PA catheters

Today’s legacy PACs involve serious risks, are complex and data is often misinterpreted — resulting in suboptimal heart failure care management and costly hospital readmissions.

High risks & discomfort for patients

2-3% serious complications

Complex to use for clinicians

Adjustments often required

Unreliable data

Data interpretation errors (up to 40%)

Wrong treatment decisions

Longueur hospital stay

23% rehospitalization within 30 days

Other monitoring devices and methods

Permanent electronic cardiac implants carry risks, long-term complications and high costs

Indirect methods (e.g. lab tests, imaging) provide delayed indirect data with limited accuracy

Non-invasive devices (wearables) have no place in the management of ADHF

Conclusion

A safer, more reliable AI-guided PAC would lead to better acute HF care management.

References:

HF STATS 2025: Heart Failure Epidemiology and Outcomes Statistics, An Updated 2025 Report from the Heart Failure Society of America
J Card Fail. 2025 DOI: https://doi.org/10.1016/j.cardfail.2025.07.007
European Heart Journal, Volume 42, Issue 36, 21 September 2021, Pages 3599–3726, https://doi.org/10.1093/eurheartj/ehab368
The Hospital Readmissions Reduction Program: Nationwide Perspectives and Recommendations: A JACC: Heart Failure Position Paper | JACC: Heart Failure, Volume 8, Issue 1,2020,Pages 1-11,ISSN 2213-1779 | https://doi.org/10.1016/j.jchf.2019.07.012

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