Clinical Evidence
Several clinical trials provide clinical evidence of a significant improvement in cardiac care and reduction in hospital stay with PAP-guided heart failure management.
MONITOR-HF clinical trial
MONITOR-HF is the third randomized, controlled clinical trial globally confirming the significant health benefit and hospital cost savings of remote PAP monitoring for patients with moderate-to-severe HF. (Ref 1,2,3,4)
Clinical evidence of improved quality of life and 44% reduction in HF hospitalizations
MONITOR-HF clinical trial enrolled 348 patients in 25 centers in the Netherlands
References
Brugts JJ et al. Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF trial): a randomised clinical trial. Lancet. 2023 May 20. doi: 10.1016/S0140-6736(23)00923-6
Brugts JJ et al. A randomised comparison of the effect of haemodynamic monitoring with CardioMEMS on quality of life and hospitalisations in heart failure patients (MONITOR-HF trial). 2020 Jan 28. doi: 10.1007/s12471-019-01341-9
ESC press release. 20 May 2023 - Remote monitoring reduces heart failure hospitalisations and improves quality of life - results from MONITOR-HF trial
Abbott press release. 24 May 2023 - European Study Finds the Abbott CardioMEMS Sensor Results in Improved Quality of Life and 44% Reduction in HF Hospitalizations
Cowie MR et al. Real-world evidence in a national health service: results of the UK CardioMEMS Post-Market Study (COAST trial). ESC HF. 2022 Feb 9. doi: 10.1002/ehf2.13748.
Brugts JJ et al. Clinical Update of the Latest Evidence for CardioMEMS Pulmonary Artery Pressure Monitoring in Patients with Chronic HF: A Promising System for Remote HF Care. Sensors (Basel). 2021 Mar 27. doi: 10.3390/s21072335
Abraham WT et al. Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomized control study (CHAMPION trial). Lancet. 2011 Feb 19;377(9766):658-66
Adamson PB et al. Pulmonary Artery Pressure–Guided Heart Failure Management Reduces 30-Day Readmissions (CHAMPION trial). Circ Heart Fail. 2016;9:e002600.
Abraham, WT et al. Pulmonary artery pressure management in heart failure patients - significantly reduces heart failure hospitalizations and mortality. vol. 65 no. 10, ACC 2015